1. Research interests:
(1) Autoimmune disease: The mechanisms and immunological therapy; Effect and mechanisms of
traditional Chinese medicine;
(2) Transplantation immunology: Protection of chronic cyclosporin A nephrotoxicity; Development
of novel immunosuppresants.
2. Current projects:
(1) The effect and mechanisms of combined transplantation of PBSCs and oteoblasts on NZB/W
F1 SLE mouse model;
(2) The protect effect and mechanisms of tranilast on chronic cyclosporin A nephrotoxicity;
(3) The mode of action of Chinese traditional medicine on SCID psoriasis model;
(4) Local administration of tranilast on rabbit hypertrophic scar model.
3. Previous projects:
(1) The mechanisms of Chloroquine in suppressing Graft-Versus-Host Disease (GVHD)
after Bone Marrow Transplantation (BMT)
(2) Differential Effect of G-CSF on Marrow and Blood-Derived Hematopoietic and
Immune Cell Populations in Healthy Human Donors
(3) Phase III Trial of Hydroxychloroquine + Standard Therapy Chronic Graft-Versus-
Host Disease.
(4) Function of NK and NKT after Haplo-identical Hematopoietic Stem Cell
Transplantation (HSCT)
(5) Investigation of dendritic cell (DC) in mediating tolerance in neonates and adults
(6) Control of immunity vs. tolerance by dendritic cells in xenotransplantation:
(7) Characterization of an alternative form of mouse IL-2 ( DIL-2)
(8) Analysis of the mode of action of a novel immunosuppressant FTY720
(9)Anergic cells generated in vitro suppress rejection response to islet allografts
(10) Antiadhesion Therapy in the rejection responses of islet allograft.
(11) Analysis of gene expression profile of high endothelial venules (HEV) and
identification of novel genes in HEV
(12) Construction of a hypertensive transgenic animal model
(1) Autoimmune disease: The mechanisms and immunological therapy; Effect and mechanisms of
traditional Chinese medicine;
(2) Transplantation immunology: Protection of chronic cyclosporin A nephrotoxicity; Development
of novel immunosuppresants.
2. Current projects:
(1) The effect and mechanisms of combined transplantation of PBSCs and oteoblasts on NZB/W
F1 SLE mouse model;
(2) The protect effect and mechanisms of tranilast on chronic cyclosporin A nephrotoxicity;
(3) The mode of action of Chinese traditional medicine on SCID psoriasis model;
(4) Local administration of tranilast on rabbit hypertrophic scar model.
3. Previous projects:
(1) The mechanisms of Chloroquine in suppressing Graft-Versus-Host Disease (GVHD)
after Bone Marrow Transplantation (BMT)
(2) Differential Effect of G-CSF on Marrow and Blood-Derived Hematopoietic and
Immune Cell Populations in Healthy Human Donors
(3) Phase III Trial of Hydroxychloroquine + Standard Therapy Chronic Graft-Versus-
Host Disease.
(4) Function of NK and NKT after Haplo-identical Hematopoietic Stem Cell
Transplantation (HSCT)
(5) Investigation of dendritic cell (DC) in mediating tolerance in neonates and adults
(6) Control of immunity vs. tolerance by dendritic cells in xenotransplantation:
(7) Characterization of an alternative form of mouse IL-2 ( DIL-2)
(8) Analysis of the mode of action of a novel immunosuppressant FTY720
(9)Anergic cells generated in vitro suppress rejection response to islet allografts
(10) Antiadhesion Therapy in the rejection responses of islet allograft.
(11) Analysis of gene expression profile of high endothelial venules (HEV) and
identification of novel genes in HEV
(12) Construction of a hypertensive transgenic animal model
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